Bordetella Vaccine Pain & Side Effects in Dogs

published on 06 December 2025
Bordetella Vaccine Pain & Side Effects in Dogs
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Bordetella Vaccine Pain & Side Effects in Dogs

Yes, the Bordetella vaccine can cause mild, temporary pain and other side effects in dogs. This is a normal immune response as the dog's body builds protection against the Bordetella bronchiseptica bacterium. These reactions are generally mild and indicate that the immune system is responding to the antigens in the vaccine, according to Bestie Paws Hospital.

Key Takeaways on Bordetella Vaccine Reactions

Key Takeaways on Bordetella Vaccine Reactions

Most side effects experienced by dogs after receiving the Bordetella vaccine are minor and temporary. They typically resolve within 24-48 hours, as noted by Bestie Paws Hospital. For dogs that frequently interact with other pets, the benefits of the Bordetella vaccine often outweigh the risks of these mild side effects.

The Bordetella vaccine is available in two main forms: injectable and intranasal (nasal spray). Each form can lead to slightly different common side effects. Understanding these differences can help dog owners know what to expect post-vaccination.

Common Side Effects

Common Side Effects

The type of side effects a dog experiences can depend on the administration method of the vaccine. Both forms are generally well-tolerated, but owners should be aware of potential reactions.

Injectable Vaccine Reactions

When a dog receives the injectable Bordetella vaccine, localized reactions are common. These are typically confined to the area where the shot was given.

  • Pain, swelling, or tenderness at the injection site: This is a very common reaction, similar to how humans might feel sore after a flu shot.
  • Mild lethargy or decreased activity: Dogs may seem a bit sleepier or less energetic for a day or two.
  • Low-grade fever: A slight increase in body temperature can occur as the immune system activates.

Intranasal Vaccine Reactions

The intranasal vaccine is administered directly into the dog's nostrils. Because it targets the respiratory system, its side effects often mimic mild respiratory symptoms.

  • Sneezing, coughing, or runny nose: These symptoms can appear as the dog's respiratory immune system responds to the vaccine, sometimes resembling mild kennel cough symptoms.
  • Mild lethargy: Similar to the injectable form, a temporary decrease in activity is possible.

"The intranasal version may cause more sneezing but fewer injection-site reactions," states Bestie Paws Hospital. This highlights the different profiles of side effects for each vaccine type.

When to See a Vet

When to See a Vet

While most side effects are mild and resolve quickly, certain symptoms warrant immediate veterinary attention. Owners should monitor their dogs closely after vaccination.

Severe or Persistent Symptoms Requiring Veterinary Care

If any of the following symptoms occur, or if mild symptoms persist beyond 48 hours, contact your veterinarian:

  • Vomiting or diarrhea: These are not typical mild reactions and could indicate a more significant issue.
  • Difficulty breathing or severe, persistent coughing: While mild coughing can occur with the intranasal vaccine, severe or labored breathing is a concern.
  • Significant swelling of the face or body: This could be a sign of an allergic reaction.
  • Hives: Raised, itchy welts on the skin also suggest an allergic response.
  • Collapse or severe weakness: Any sudden and profound weakness or collapse is an emergency.
  • Symptoms lasting longer than 48 hours: If mild lethargy or respiratory symptoms don't improve within two days, a vet visit is advisable.

According to Bestie Paws Hospital, if a dog experiences vomiting, difficulty breathing, or severe swelling, a vet should be called immediately.

Post-Vaccination Care Checklist

Providing appropriate care after vaccination can help ensure your dog's comfort and aid in their recovery from any mild side effects.

  • Monitor Your Dog: Pay close attention to your dog's behavior, appetite, and energy levels for a few days after the vaccine.
  • Provide Comfort: Ensure your dog has a quiet, warm, and comfortable place to rest. Minimize disruptions.
  • Offer Fresh Water: Keep fresh water readily available to ensure your dog stays hydrated, especially if they experience a low-grade fever.
  • Limit Strenuous Activity: Avoid intense exercise, long walks, or vigorous play for 24-48 hours post-vaccination. Allow them to rest and recover.
  • Avoid Touching Injection Site: If your dog received an injectable vaccine, try to avoid touching or putting pressure on the injection site to prevent further discomfort.

Bordetella Vaccine Necessity

The decision to vaccinate against Bordetella often depends on a dog's lifestyle and potential exposure to the bacteria. Veterinarians evaluate environmental risks to recommend individual vaccination strategies, according to Great Pet Care.

High-Risk Dogs and Exposure

The Bordetella vaccine is particularly recommended for dogs that are socially active and frequently interact with other canines.

  • Recommended for dogs frequently exposed to other dogs: This includes those attending daycare, boarding facilities, dog parks, grooming appointments, or training classes.
  • "If your beloved pup has a very social lifestyle they are at a higher risk of catching bordetella (also called kennel cough) from their doggy daycare or at the dog park and should receive the Bordetella vaccine to help prevent it," states Dog Bordetella Vaccine | Are There Any Reactions To It?.
  • Dogs living in large apartment communities or participating in pet therapy also fall into this high-risk category, as per Great Pet Care.

Kennel Cough Prevention

The primary purpose of the Bordetella vaccine is to protect against kennel cough.

  • Protects against Bordetella bronchiseptica: This bacterium is a common cause of kennel cough, a highly contagious respiratory disease.
  • Kennel cough is a blanket term for various infectious respiratory illnesses, characterized by inflammation of the trachea and bronchi, according to Chewy.
  • Signs of kennel cough include a persistent honking cough and nasal discharge, similar to a human cold, and it spreads easily from dog to dog, Chewy explains.
  • The vaccine helps protect against this specific bacterium and is widely available to keep dogs safe from kennel cough, according to Chewy.

Preventing Serious Complications

While many cases of kennel cough are mild, the disease can sometimes lead to more severe health issues.

  • Prevents potential progression to pneumonia: Especially in puppies or dogs with compromised immune systems, kennel cough can develop into pneumonia.
  • The disease can cause a lingering cough and decreased appetite in adult dogs, but serious disease like pneumonia in puppies and dogs with compromised immune systems, according to Great Pet Care.
  • Simple respiratory infections can easily evolve into dangerous and life-threatening conditions, highlighting the importance of vaccination to protect dogs and their companions, as noted by Dog Bordetella Vaccine | Are There Any Reactions To It?.

❓ Frequently Asked Questions

How long do side effects typically last?

Most side effects are mild and temporary, resolving within 24-48 hours after vaccination.

Is the intranasal vaccine safer?

The intranasal version may cause more sneezing, coughing, or a runny nose, but it typically results in fewer injection-site reactions compared to the injectable form.

Can the vaccine give my dog kennel cough?

No, the Bordetella vaccine contains inactivated or attenuated (weakened) forms of the bacteria. It stimulates immunity without causing the full disease.

Is the Bordetella vaccine a core vaccine?

No, it is considered a "lifestyle" or non-core vaccine. It is recommended based on a dog's individual risk of exposure to the *Bordetella bronchiseptica* bacterium, rather than being universally required.

What if my dog is a puppy or has health issues?

It is crucial to discuss vaccination with your veterinarian. Puppies (especially those under 8 weeks for the injectable vaccine, though the nasal spray can be given as young as 6 weeks) or dogs with compromised immune systems may have different considerations or require a tailored vaccination plan. The Bordetella vaccine is a safe and effective tool for protecting dogs, particularly those with active social lives, from kennel cough and its potential complications. While mild, temporary side effects like pain, lethargy, or respiratory symptoms can occur, these are normal immune responses and usually resolve quickly. Owners should monitor their dogs closely after vaccination and contact their vet if severe or persistent symptoms arise, ensuring their pet receives the necessary protection with minimal discomfort.

✍️ Written by

The PawGroom.AI Team

Expert guidance on dog grooming, health, and style—powered by AI and trusted by professional groomers.

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